Cardiovascular disease, including heart disease and stroke, knows no borders and it is the leading global cause of death with more than 17.9 million deaths each year.1 The origins of cardiovascular disease are multifactorial and are ideally address by the functional/integrative medicine clinician. The influence of nutrition, physical activity, metabolic factors, and emotional state on heart health is unmistakable. Aside from these factors, environmental toxin exposure, infections, obesity, dental conditions, and sleep habits can all contribute to cardiovascular disease.